Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107883 | 0.83 | MAPK1 (0.36) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL6572302 | 0.79 | PRKCI (0.39) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL6572254 | 0.76 | CYP3A4 (0.43) | SMN1; SMN2RAB9ATDP1MAPK1L3MBTL1 | |
| SCHEMBL6570974 | 0.75 | NSD2 (0.41) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL6570745 | 0.75 | BRD4 (0.39) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL3784887 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL16543023 | 0.73 | CASP1 (0.42) | SMN1; SMN2TDP1MAPTMAPK1CYP3A4 | |
| SCHEMBL3793482 | 0.73 | MAPT (0.52) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL3791002 | 0.73 | MAP4K4 (0.47) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 | |
| SCHEMBL3789831 | 0.72 | MAPT (0.41) | SMN1; SMN2RAB9ATDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |