Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599128 | 0.84 | MEN1 (0.47) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL1323122 | 0.84 | CA12 (0.55) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL12593466 | 0.84 | CA9 (0.46) | TSHRAPOBEC3AHTTAPOBEC3GMEN1 | |
| SCHEMBL11521097 | 0.82 | TSHR (0.44) | TSHRAPOBEC3AHTTAPOBEC3GTDP1 | |
| Hydrochloric Acid SCHEMBL9550013 | 0.81 | TSHR (0.63) | TSHRAPOBEC3AHTTAPOBEC3GPOLB | |
| SCHEMBL14720035 | 0.81 | TSHR (0.46) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL2172500 | 0.80 | ERN1 (0.54) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL15263986 | 0.80 | KDM4E (0.53) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL20662812 | 0.79 | KDM4E (0.58) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E | |
| SCHEMBL19878220 | 0.79 | L3MBTL1 (0.47) | TSHRAPOBEC3AHTTAPOBEC3GKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264605-A1 | Multi-Functional Ionic Liquid Compositions for Overcoming Polymorphism and Imparting Improved Properties for Active Pharmaceutical, Biological, Nutritional, and Energetic Ingredients | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2012-10-18 | — | — | US | disclosed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |
| US-5006533-A | Neuroleptic agents, side effect reduction | BOEHRINGER INGELHEIM GMBH (DE) | 1991-04-09 | — | — | US | disclosed |
| US-5006533-A | Neuroleptic agents, side effect reduction | BOEHRINGER INGELHEIM GMBH (DE) | 1991-04-09 | — | — | US | disclosed |
| US-5006533-A | Neuroleptic agents, side effect reduction | BOEHRINGER INGELHEIM GMBH (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0258800-A3 | 3-BROMO-2,6-DIMETHOXYBENZAMIDES, THEIR PREPARATION AND USE | BOEHRINGER INGELHEIM KG (DE) | 1989-08-16 | — | — | EP | disclosed |
| EP-0258800-A2 | 3-Bromo-2,6-dimethoxybenzamides, their preparation and use | BOEHRINGER INGELHEIM KG (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258800-A2 | 3-Bromo-2,6-dimethoxybenzamides, their preparation and use | BOEHRINGER INGELHEIM KG (DE) | 1988-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264605-A1 | Multi-Functional Ionic Liquid Compositions for Overcoming Polymorphism and Imparting Improved Properties for Active Pharmaceutical, Biological, Nutritional, and Energetic Ingredients | SLC5A6, PNLIP, IPMK | TSHR 4253/4885APOBEC3A 1483/4885HTT 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.