Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570857 | 0.86 | PTGER4 (0.39) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL6571575 | 0.85 | ALDH1A1 (0.41) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL6572041 | 0.84 | GAA (0.47) | ALOX15HSD17B10ALDH1A1HDAC2KDM4E | |
| SCHEMBL6572277 | 0.84 | KDM4E (0.40) | HSD17B10ALDH1A1KDM4EPTGER4 | |
| SCHEMBL6572982 | 0.84 | PTGER4 (0.40) | CYP3A4ALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL6572273 | 0.83 | CDK1 (0.46) | KIF11ALOX5APFEN1HDAC2SLC1A3 | |
| SCHEMBL6571144 | 0.83 | ADRB2 (0.44) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL6571410 | 0.82 | ALDH1A1 (0.46) | CYP1A2CYP3A4TSHRCYP2C19HSD17B10 | |
| SCHEMBL6573249 | 0.81 | PTGER4 (0.39) | CYP1A2CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL6572594 | 0.80 | PTGER4 (0.57) | CYP3A4ALDH1A1HDAC2KDM4ECFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |