SCHEMBL6572241

SCHEMBL6572241

Cc1ccc(S(=O)(=O)OCc2ccc3ccccc3n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
GFER P55789 1/20 0.47
CYSLTR1 Q9Y271 4/20 0.47
CYSLTR2 Q9NS75 2/20 0.47
PDE10A Q9Y233 3/20 0.46
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
GPBAR1 Q8TDU6 2/20 0.42
ADAMTS4 O75173 1/20 0.42
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041498 1.00 KDM4E (0.50) KDM4EKEAP1NFE2L2GFERCYSLTR1
SCHEMBL27564634 0.83 KEAP1 (0.51) KDM4EKEAP1NFE2L2PDE10AALDH1A1
SCHEMBL25318427 0.82 KEAP1 (0.44) KDM4EKEAP1NFE2L2ALDH1A1GAA
SCHEMBL31580472 0.81 AR (0.48) CYSLTR1PDE10A
Quinaldine SCHEMBL10601068 0.80 CYP1A2 (0.51) KDM4EKEAP1NFE2L2GFERALDH1A1
SCHEMBL26771412 0.79 CYSLTR1 (0.54) CYSLTR1CYSLTR2PDE10AGPBAR1CYP1A2
SCHEMBL6627155 0.78 KEAP1 (0.46) KDM4EKEAP1NFE2L2GFERALDH1A1
SCHEMBL28330143 0.78 KDM4E (0.54) KDM4EKEAP1NFE2L2GFERALDH1A1
SCHEMBL8237354 0.77 KEAP1 (0.48) KDM4EKEAP1NFE2L2GFERPDE10A
SCHEMBL4531537 0.77 TP53 (0.47) KDM4ECYSLTR1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115522186-B Chemical nickel plating solution for glass substrate and chemical nickel plating process thereof 深圳创智芯联科技股份有限公司 2023-04-11 CN claimed
CN-115522186-A Chemical nickel plating solution for glass substrate and chemical nickel plating process thereof 深圳创智芯联科技股份有限公司 2022-12-27 CN claimed
CN-115522186-B Chemical nickel plating solution for glass substrate and chemical nickel plating process thereof 深圳创智芯联科技股份有限公司 2023-04-11 CN disclosed
CN-115522186-A Chemical nickel plating solution for glass substrate and chemical nickel plating process thereof 深圳创智芯联科技股份有限公司 2022-12-27 CN disclosed
CN-105814040-B The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative 癌症研究科技有限公司 2019-07-30 CN disclosed
CN-101230066-A Antidepressant piperidine derivatives of heterocycle-fused benzodioxans WYETH CORP (US) 2008-07-30 CN disclosed
CN-101143867-A Antidepressant indolealkyl derivatves of heterocyclefused benzodioxan methylamines WYETH CORP (US) 2008-03-19 CN disclosed
CN-100358898-C Antidepressant indolealkyl derivatives of heterocycle-fused benzodi * alkylmethylamines WYETH CORP (US) 2008-01-02 CN disclosed
CN-100352820-C Antidepressant azacyclomethyl derivatives of heterocycle-fused benzodioxans WYETH CORP (US) 2007-12-05 CN disclosed
CN-100351256-C Antidepressant piperidine derivatives of heterocycle-fused benzodi * alkanes WYETH CORP (US) 2007-11-28 CN disclosed
CN-1309722-C Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans WYETH CORP (US) 2007-04-11 CN disclosed
CN-1701076-A Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans WYETH CORP (US) 2005-11-23 CN disclosed
CN-1701075-A Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines WYETH CORP (US) 2005-11-23 CN disclosed
CN-1681821-A Antidepressivt virkende cykloalkylaminderivater AV heterocykle-kondenserte benzodioksaner WYETH CORP (US) 2005-10-12 CN disclosed
CN-1681820-A Antidepressant piperidine derivatives of heterocycle-fused benzodioxans WYETH CORP (US) 2005-10-12 CN disclosed
CN-1561337-A Stereospecific process for the synthesis of 2-yl chroman derivatives WYETH CORP (US) 2005-01-05 CN disclosed
EP-1432694-A1 STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES Wyeth (US) 2004-06-30 EP disclosed
WO-2003031428-A1 STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES WYETH (US) 2003-04-17 WO disclosed