Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CD4 | P01730 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050463 | 0.93 | KEAP1 (0.40) | KEAP1NFE2L2ALDH1A1KDM4EHPGD | |
| SCHEMBL3645222 | 0.90 | KEAP1 (0.40) | KEAP1NFE2L2ALDH1A1KDM4EHPGD | |
| SCHEMBL16050543 | 0.88 | PSMD10 (0.39) | KEAP1NFE2L2ALDH1A1KDM4EHPGD | |
| SCHEMBL16050461 | 0.87 | KEAP1 (0.38) | KEAP1NFE2L2ALDH1A1KDM4EHPGD | |
| SCHEMBL17258376 | 0.87 | ALDH1A1 (0.36) | KEAP1NFE2L2ALDH1A1KDM4EHPGD | |
| SCHEMBL3777059 | 0.83 | SYK (0.50) | ALDH1A1KDM4EKMT2APTGS2 | |
| SCHEMBL18977857 | 0.83 | KMT2A (0.40) | KEAP1NFE2L2ALDH1A1VDRMEN1 | |
| SCHEMBL29995677 | 0.83 | SYK (0.50) | ALDH1A1KDM4EKMT2APTGS2 | |
| SCHEMBL30041498 | 0.82 | KDM4E (0.50) | KEAP1NFE2L2ALDH1A1KDM4EGAA | |
| SCHEMBL6572241 | 0.82 | KDM4E (0.50) | KEAP1NFE2L2ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101475-A1 | MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS | VIO CHEMICALS AG (CH) | 2025-03-27 | — | — | US | claimed |
| WO-2023126510-A1 | MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS | VIO CHEMICALS AG (CH) | 2023-07-06 | — | — | WO | claimed |
| US-20250101475-A1 | MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS | VIO CHEMICALS AG (CH) | 2025-03-27 | — | — | US | disclosed |
| WO-2023126510-A1 | MONOOXYGENASE MUTANTS FOR BIOSYNTHESIS OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE AND A METHOD FOR PREPARATION OF 2,6-BIS(HYDROXYMETHYL)PYRIDINE USING THE SAID MONOOXYGENASE MUTANTS | VIO CHEMICALS AG (CH) | 2023-07-06 | — | — | WO | disclosed |
| CN-111056925-B | Chiral diol compound, chiral crown ether compound and preparation method thereof | 上海交通大学 | 2023-03-21 | — | — | CN | disclosed |