Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573022 | 0.86 | GRIA4 (0.47) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6763704 | 0.85 | ALDH1A1 (0.51) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6571852 | 0.82 | PTGS2 (0.66) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6571967 | 0.82 | PTGS2 (0.45) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6763717 | 0.81 | ALDH1A1 (0.44) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6761044 | 0.80 | ALDH1A1 (0.49) | PTGS2ALDH1A1MTNR1AKDM4EDYRK3 | |
| SCHEMBL6763745 | 0.78 | GRIA4 (0.48) | PTGS2SLC2A1SMN1; SMN2CA12CA1 | |
| SCHEMBL6759300 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MTNR1AHSD17B10NPC1 | |
| SCHEMBL6763747 | 0.78 | ALDH1A1 (0.47) | PTGS2SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL761730 | 0.77 | NQO2 (0.54) | SMN1; SMN2CA12CA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
| EP-1409452-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002098846-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | PTGS2 959/4885SLC2A1 488/4885SMN1; SMN2 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.