Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914480 | 0.78 | CYP19A1 (0.51) | RECQLLMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL6575768 | 0.77 | ALDH1A1 (0.50) | LMNASMN1; SMN2TDP1MAPTMEN1 | |
| SCHEMBL6572322 | 0.76 | MAPT (0.41) | RECQLLMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL28343073 | 0.76 | HTT (0.57) | LMNASMN1; SMN2TDP1HTTMAPT | |
| SCHEMBL13253426 | 0.73 | TDP1 (0.56) | LMNANPSR1TDP1L3MBTL1HTT | |
| SCHEMBL2061679 | 0.72 | PTGDR2 (0.61) | RECQLLMNASMN1; SMN2NPSR1TDP1 | |
| SCHEMBL27708625 | 0.71 | GRIK1 (0.51) | LMNASMN1; SMN2NPSR1TDP1L3MBTL1 | |
| SCHEMBL1744862 | 0.70 | ALDH1A1 (0.53) | LMNANPSR1TDP1L3MBTL1HTT | |
| SCHEMBL2060780 | 0.70 | ALDH1A1 (0.53) | LMNASMN1; SMN2NPSR1TDP1L3MBTL1 | |
| SCHEMBL2061280 | 0.70 | MAPT (0.50) | RECQLLMNASMN1; SMN2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |