SCHEMBL6572334

SCHEMBL6572334

Clc1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2ccc(Cl)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.57
KDM4E B2RXH2 2/20 0.57
ATM Q13315 1/20 0.57
BIRC5 O15392 1/20 0.42
USP14 P54578 4/20 0.41
MAPT P10636 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
LIG1 P18858 1/20 0.40
TP53 P04637 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
POLB P06746 1/20 0.39
MAT2A P31153 1/20 0.39
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
PMM2 O15305 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31045466 0.92 KDM4E (0.67) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL12546471 0.92 KDM4E (0.67) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL27241686 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL9971736 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL11899745 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL13562922 0.90 KDM4E (0.70) L3MBTL1KDM4EATMMAPTTDP1
SCHEMBL24374230 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL11899756 0.89 L3MBTL1 (0.57) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL19863546 0.86 KDM4E (0.59) L3MBTL1KDM4EATMBIRC5USP14
SCHEMBL22877774 0.86 KDM4E (0.59) L3MBTL1KDM4EATMBIRC5USP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP claimed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP claimed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US claimed
EP-0908787-B1 Indolocarbazole Photoconductors XEROX CORP (US) 2004-04-14 EP disclosed
EP-0908787-A2 Indolocarbazole Photoconductors Xerox Corporation (US) 1999-04-14 EP disclosed
US-5843607-A Indolocarbazole photoconductors XEROX CORPORATION (US) 1998-12-01 US disclosed