SCHEMBL9971736

SCHEMBL9971736

Clc1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ATM Q13315 1/20 0.55
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 3/20 0.41
TP53 P04637 1/20 0.41
BIRC5 O15392 1/20 0.41
USP14 P54578 4/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LIG1 P18858 1/20 0.39
POLB P06746 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PMM2 O15305 1/20 0.37
G6PD P11413 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27241686 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL6572334 0.91 L3MBTL1 (0.57) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL19721759 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL21578475 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL16848794 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL29457635 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL31045466 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL12546471 0.90 KDM4E (0.67) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL12546465 0.88 L3MBTL1 (0.50) L3MBTL1KDM4EATMMEN1LMNA
SCHEMBL21215244 0.87 KDM4E (0.48) L3MBTL1KDM4EATMMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153273-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153273-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120153273-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, AP1M1, AP2M1 L3MBTL1 94/4885KDM4E 4448/4885ATM 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.