Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572600 | 0.93 | PDE10A (0.59) | PDE10ATDP1TP53CYP1A2CYP2C19 | |
| SCHEMBL6573367 | 0.86 | PDE10A (0.63) | PDE10ATDP1TP53ALDH1A1ALOX15 | |
| SCHEMBL6572250 | 0.86 | PDE10A (0.61) | PDE10ATDP1TP53CYP2C19ALDH1A1 | |
| SCHEMBL23222817 | 0.84 | TDP1 (0.52) | TDP1TP53CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6572548 | 0.83 | PDE10A (0.59) | PDE10ATDP1TP53CYP1A2CYP2C19 | |
| SCHEMBL9056966 | 0.83 | ALOX15 (0.48) | TDP1TP53CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL14363376 | 0.82 | TRPA1 (0.50) | TDP1TP53CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6572281 | 0.82 | PDE10A (0.50) | PDE10ATDP1TP53CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6781826 | 0.81 | PDE10A (0.57) | PDE10ATDP1TP53ALDH1A1ALOX15 | |
| SCHEMBL6781112 | 0.81 | PDE10A (0.57) | PDE10ATDP1TP53ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | claimed |