Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576742 | 0.92 | ADORA1 (0.53) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 | |
| SCHEMBL6573247 | 0.86 | ADORA3 (0.61) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6573236 | 0.86 | ADORA3 (0.61) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6572907 | 0.86 | ADORA3 (0.65) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6576714 | 0.84 | ADORA1 (0.65) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6574622 | 0.84 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 | |
| SCHEMBL6797276 | 0.84 | ADORA2A (0.65) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 | |
| SCHEMBL6576651 | 0.82 | ADORA1 (0.65) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 | |
| SCHEMBL6576982 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 | |
| SCHEMBL6575289 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |