Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371728 | 0.90 | MEN1 (0.70) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL31418722 | 0.90 | MEN1 (0.70) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| Bicarbonate SCHEMBL5503301 | 0.88 | CYP19A1 (0.65) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL9264415 | 0.87 | TSHR (0.67) | CYP19A1CYP11B1CYP11B2MAPTKMT2A | |
| SCHEMBL15814707 | 0.86 | MAPT (0.62) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL6573349 | 0.84 | PTGDR2 (0.64) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL7476491 | 0.84 | PTGDR2 (0.64) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL10744505 | 0.83 | CTSV (0.50) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL25289864 | 0.83 | MAPT (0.58) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL30498823 | 0.83 | MEN1 (0.55) | CYP19A1CYP11B1CYP11B2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| CN-1134410-C | Amine derivatives, process for their preparation and their use as antiarrhythmic agents | �й�ʯ����������ʯ�ͻ����������ι� | 2004-01-14 | — | — | CN | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| CN-1169141-A | Novel amine derivatives, process for their preparation and their use as antiarrhythmic agents | C & C RESEARCH LABS (KR) | 1997-12-31 | — | — | CN | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |