Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476491 | 1.00 | PTGDR2 (0.64) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| Bicarbonate SCHEMBL5503301 | 0.91 | CYP19A1 (0.65) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL371728 | 0.90 | MEN1 (0.70) | CYP19A1MEN1KMT2AMAPTCYP11B1 | |
| SCHEMBL31418722 | 0.90 | MEN1 (0.70) | CYP19A1MEN1KMT2AMAPTCYP11B1 | |
| SCHEMBL3480872 | 0.89 | PTGDR2 (0.69) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6575840 | 0.86 | CYP19A1 (0.57) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6572912 | 0.84 | CYP19A1 (0.62) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| Bicarbonate SCHEMBL5500204 | 0.83 | CYP19A1 (0.63) | CYP19A1MEN1KMT2AMAPTCYP11B1 | |
| SCHEMBL7156431 | 0.83 | PTGDR2 (0.59) | PTGDR2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL2063456 | 0.82 | MAPT (0.67) | CYP19A1MEN1KMT2AMAPTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |