Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880310 | 0.94 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL6579182 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL17798624 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL28080744 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL9679306 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5943351 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL20109817 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL735278 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL6642914 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL3222768 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003995-A | Pyrone-[3, 4-b] indole derivative and synthetic method thereof | UNIV SHANGHAI JIAOTONG | 2014-08-27 | — | — | CN | claimed |
| US-11897881-B1 | Substituted pyrido[3,4-b]indole-3-carboxylic acids as CK2 inhibitors | King Faisal University (SA) | 2024-02-13 | — | — | US | disclosed |
| CN-104003995-B | Pyranone also [3,4-b] indole derivatives and synthetic method thereof | 上海交通大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-104003995-A | Pyrone-[3, 4-b] indole derivative and synthetic method thereof | UNIV SHANGHAI JIAOTONG | 2014-08-27 | — | — | CN | disclosed |
| CN-102627563-B | Phthalic acid compound, its preparation method and application | UNIV SICHUAN | 2014-07-23 | — | — | CN | disclosed |
| CN-102627563-A | Phthalic acid compound, its preparation method and application | UNIV SICHUAN | 2012-08-08 | — | — | CN | disclosed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | disclosed |
| US-6187285-B1 | IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. | GUERBET (FR) | 2001-02-13 | — | — | US | disclosed |
| WO-1999011606-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |
| US-5563273-A | COLOR CHANGE AGENT | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0431547-B1 | Charge transfer salts and uses thereof | IBM (US) | 1994-09-21 | — | — | EP | disclosed |
| US-5179467-A | Color for visual displays in electrochemical cells | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1991008507-A1 | CHARGE TRANSFER SALTS AND USES THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-06-13 | — | — | WO | disclosed |
| EP-0431547-A2 | Charge transfer salts and uses thereof | International Business Machines Corporation (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4866095-A | 1,8-dihydroxy-9-anthrones for treating warts or psoriasis | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIEQUES C.I.R.D. (FR) | 1989-09-12 | — | — | US | disclosed |
| US-4558069-A | TREATMENT OF SKIN DISORDERS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1985-12-10 | — | — | US | disclosed |
| US-4465688-A | FOR TREATMENT OF SKIN DISORDERS | GROUPEMENT D'INTERET ECONOMIQUE CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1984-08-14 | — | — | US | disclosed |
| US-4464301-A | FOR TREATMENT OF PSORIASIS | GROUPEMENT D'INTERET ECONOMIQUE CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1984-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897881-B1 | Substituted pyrido[3,4-b]indole-3-carboxylic acids as CK2 inhibitors | CSNK2A3, CDK2, SKP2 | ALDH1A1 2699/4885TDP1 2845/4885MAPK1 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.