Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572835 | 0.94 | ADORA3 (0.48) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6575215 | 0.89 | ADORA1 (0.46) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6575222 | 0.89 | ADORA1 (0.46) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574580 | 0.88 | ADORA3 (0.47) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574576 | 0.88 | ADORA3 (0.47) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574592 | 0.85 | ADORA3 (0.47) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574589 | 0.85 | ADORA3 (0.47) | SLC29A1ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6575179 | 0.82 | ADORA3 (0.42) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6575172 | 0.82 | ADORA3 (0.42) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6573870 | 0.77 | ADORA3 (0.60) | SLC29A1ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |