Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574592 | 1.00 | ADORA3 (0.47) | ADORA3ADORA2AADORA1NFKB1THPO | |
| SCHEMBL6575179 | 0.92 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6575172 | 0.92 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6574576 | 0.90 | ADORA3 (0.47) | ADORA3ADORA2AADORA1NFKB1THPO | |
| SCHEMBL6574580 | 0.90 | ADORA3 (0.47) | ADORA3ADORA2AADORA1NFKB1THPO | |
| SCHEMBL6575222 | 0.89 | ADORA1 (0.46) | ADORA3ADORA2AADORA1TSHRADORA2B | |
| SCHEMBL6575215 | 0.89 | ADORA1 (0.46) | ADORA3ADORA2AADORA1TSHRADORA2B | |
| SCHEMBL6572835 | 0.88 | ADORA3 (0.48) | ADORA3ADORA2AADORA1NFKB1THPO | |
| SCHEMBL6572980 | 0.85 | SLC29A1 (0.51) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL6574202 | 0.77 | ADORA3 (0.52) | ADORA3ADORA2AADORA1NFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |