Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573481 | 0.87 | PDE10A (0.52) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL6572324 | 0.85 | PDE10A (0.54) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL5687750 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL5688007 | 0.85 | TSHR (0.48) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL3786791 | 0.83 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL6011189 | 0.83 | NR1I2 (0.47) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL5133404 | 0.82 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL3791666 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL19486098 | 0.80 | BRD4 (0.46) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL2068581 | 0.80 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110126396-B | Laminated composite damping sheet and preparation method thereof | 浙江工业大学 | 2022-01-14 | — | — | CN | claimed |
| CN-112358667-A | Rubber composition and preparation method and application thereof | 中国第一汽车股份有限公司 | 2021-02-12 | — | — | CN | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| CN-112358667-B | Rubber composition and preparation method and application thereof | 中国第一汽车股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-110126396-B | Laminated composite damping sheet and preparation method thereof | 浙江工业大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-112358667-A | Rubber composition and preparation method and application thereof | 中国第一汽车股份有限公司 | 2021-02-12 | — | — | CN | disclosed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |