Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573481 | 0.87 | PDE10A (0.52) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL3791666 | 0.85 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL6572324 | 0.85 | PDE10A (0.54) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL29518540 | 0.84 | PDE10A (0.64) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL9402506 | 0.84 | PDE10A (0.64) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL30880219 | 0.84 | PDE10A (0.64) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL6782469 | 0.84 | PDE10A (0.45) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL6573855 | 0.84 | PDE10A (0.45) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL6573277 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL28136101 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | claimed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-6749644-B2 | DEVELOPER AND COUPLER; WIDE RANGE OF DIFFERENT COLOR SHADES FROM BLOND TO BROWN, PURPLE, VIOLET AND EVEN BLUE AND BLACK; INTENSITY | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-14 | — | — | US | disclosed |
| EP-1208077-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002002507-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885L3MBTL1 3838/4885PDE10A 3386/4885 |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | AHR, KRT18, HMOX2 | ALDH1A1 20/4885L3MBTL1 4512/4885PDE10A 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.