Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | VDR | P11473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570871 | 0.85 | AR (0.36) | ARVDRGAAMAPTMAPK1 | |
| SCHEMBL6571036 | 0.84 | VDR (0.36) | ARVDRGAAMAPTMAPK1 | |
| SCHEMBL6571001 | 0.83 | LMNA (0.41) | ARVDRGAAMAPTMAPK1 | |
| SCHEMBL6572349 | 0.82 | AR (0.33) | POLBARVDRGAAMAPT | |
| SCHEMBL6571998 | 0.82 | LCK (0.34) | ARVDRMAPK1TSHRCASP1 | |
| SCHEMBL6574192 | 0.81 | POLB (0.49) | POLBGAAMAPTMAPK1SIGMAR1 | |
| SCHEMBL6573016 | 0.81 | AR (0.34) | ARVDRGAAMAPTMAPK1 | |
| SCHEMBL6570818 | 0.81 | AR (0.33) | ARVDR | |
| SCHEMBL3863528 | 0.81 | VDR (0.47) | ARVDRMAPTMAPK1LMNA | |
| SCHEMBL6571431 | 0.80 | AR (0.36) | POLBARVDRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |