Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13215153 | 0.87 | POLB (0.57) | MAPTKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL7476491 | 0.86 | PTGDR2 (0.64) | CYP19A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6573349 | 0.86 | PTGDR2 (0.64) | CYP19A1MAPTMEN1KMT2ASMN1; SMN2 | |
| Bicarbonate SCHEMBL5503301 | 0.84 | CYP19A1 (0.65) | CYP19A1MAPTMEN1KMT2ACYP11B1 | |
| SCHEMBL371728 | 0.84 | MEN1 (0.70) | CYP19A1MAPTMEN1KMT2ACYP11B1 | |
| SCHEMBL31418722 | 0.84 | MEN1 (0.70) | CYP19A1MAPTMEN1KMT2ACYP11B1 | |
| SCHEMBL3536740 | 0.83 | ALDH1A1 (0.60) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL20042055 | 0.83 | ALDH1A1 (0.55) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL7914606 | 0.82 | NPC1 (0.56) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL13215072 | 0.81 | KDM4E (0.52) | CYP19A1MAPTLMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| CN-1134410-C | Amine derivatives, process for their preparation and their use as antiarrhythmic agents | �й�ʯ����������ʯ�ͻ����������ι� | 2004-01-14 | — | — | CN | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| CN-1169141-A | Novel amine derivatives, process for their preparation and their use as antiarrhythmic agents | C & C RESEARCH LABS (KR) | 1997-12-31 | — | — | CN | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |