⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597404 | 0.69 | — | — | |
| SCHEMBL292333 | 0.69 | — | — | |
| SCHEMBL2766782 | 0.66 | LMNA (0.36) | — | |
| SCHEMBL255119 | 0.65 | — | — | |
| SCHEMBL2551980 | 0.64 | KMT2A (0.40) | — | |
| SCHEMBL232012 | 0.63 | MAPT (0.55) | — | |
| SCHEMBL293669 | 0.62 | — | — | |
| SCHEMBL197523 | 0.61 | MAPT (1.00) | — | |
| SCHEMBL10049904 | 0.61 | — | — | |
| SCHEMBL10991854 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365592-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2023-11-16 | — | — | US | disclosed |
| EP-1120388-B1 | Use of pyrazol derivatives as nitrification inhibitors | BASF AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-0917526-B1 | USE OF POLYACIDS TO TREAT MINERAL FERTILIZERS CONTAINING A NITRIFICATION INHIBITOR | BASF AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-1120388-A1 | Use of pyrazol derivatives as nitrification inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-01 | — | — | EP | disclosed |
| EP-0917526-A2 | NEW NITRIFICATION INHIBITORS AND THE USE OF POLYACIDS TO TREAT MINERAL FERTILIZERS CONTAINING A NITRIFICATION INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998005607-A2 | NEW NITRIFICATION INHIBITORS AND THE USE OF POLYACIDS TO TREAT MINERAL FERTILIZERS CONTAINING A NITRIFICATION INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-12 | — | — | WO | disclosed |