Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473054 | 0.77 | NOTUM (0.39) | NOTUMGLRA3GLRBASPHDAO | |
| SCHEMBL1082810 | 0.73 | NOTUM (1.00) | NOTUMHTTSMN1; SMN2DAOKDM4E | |
| SCHEMBL2804501 | 0.71 | NOTUM (0.65) | NOTUMHTTSMN1; SMN2KDM4E | |
| SCHEMBL21738239 | 0.70 | — | — | |
| SCHEMBL6256617 | 0.69 | NOTUM (0.49) | NOTUMTAS2R14ASPHKDM4E | |
| SCHEMBL31748649 | 0.68 | NOTUM (0.73) | NOTUMHTTSMN1; SMN2DAOKDM4E | |
| SCHEMBL17897636 | 0.67 | P2RX7 (0.36) | SMN1; SMN2KDM4E | |
| SCHEMBL7685414 | 0.67 | NOTUM (0.59) | NOTUMHTTSMN1; SMN2 | |
| SCHEMBL27765397 | 0.65 | KDM4E (0.45) | NOTUMTAS2R14ALKBH5ASPHDAO | |
| SCHEMBL420887 | 0.65 | RXRA (0.46) | NOTUMTAS2R14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490378-A1 | SILICONATED PHENYL AMIDES DERIVATIVES USEFUL AS MICROBIOCIDE | Syngenta Participations AG (CH) | 2004-12-29 | — | — | EP | disclosed |
| EP-1480955-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003080628-A1 | SILICONATED PHENYL AMIDES DERIVATIVES USEFUL AS MICROBIOCIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2003-10-02 | — | — | WO | disclosed |
| WO-2003074491-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-12 | — | — | WO | disclosed |