SCHEMBL6204342

SCHEMBL6204342

CN(Cc1ccccn1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPT P10636 1/20 0.52
LIN28A Q9H9Z2 1/20 0.52
KCNA5 P22460 1/20 0.51
ALDH1A1 P00352 6/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 3/20 0.49
CYP3A4 P08684 1/20 0.49
PTPRA P18433 1/20 0.49
CA2 P00918 1/20 0.48
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427048 0.86 SMN1; SMN2 (0.52) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL13211426 0.85 KMT2A (0.51) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL7976764 0.84 SMN1; SMN2 (0.50) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL427047 0.84 SMN1; SMN2 (0.50) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL7976763 0.84 SMN1; SMN2 (0.50) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL2755865 0.83 KDM4E (0.62) KDM4ETDP1ALDH1A1KMT2ACYP1A2
SCHEMBL12313339 0.83 NTRK1 (0.51) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL28923770 0.81 L3MBTL1 (0.60) SMN1; SMN2TDP1MAPTLIN28AKCNA5
SCHEMBL24316287 0.81 CYP1A2 (0.52) KDM4ESMN1; SMN2TDP1MAPTLIN28A
SCHEMBL676887 0.81 SMN1; SMN2 (0.47) KDM4ESMN1; SMN2TDP1MAPTLIN28A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699557-B1 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS BIOTA SCIENT MANAGEMENT (AU) 2017-08-16 EP claimed
EP-1399436-B1 OXYTOCIN AGONISTS FERRING BV (NL) 2005-03-16 EP disclosed
US-20040235753-A1 Oxytocin agonists PITT GRAY ROBERT WILLIAM (GB) 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235753-A1 Oxytocin agonists OXTR, GNRHR, PRLHR KDM4E 4329/4885SMN1; SMN2 840/4885TDP1 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.