Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537879 | 0.76 | DRD2 (0.53) | DRD2NPC1RAB9AMAPTSTAT1 | |
| SCHEMBL19222078 | 0.76 | MEN1 (0.74) | DRD2SIGMAR1MEN1KMT2ASLC18A3 | |
| SCHEMBL11499121 | 0.75 | MEN1 (0.68) | DRD2SIGMAR1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11501364 | 0.74 | MEN1 (0.66) | DRD2SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL27547734 | 0.73 | NPC1 (0.49) | DRD2NPC1RAB9AMAPTSTAT1 | |
| SCHEMBL11440535 | 0.72 | DRD2 (0.53) | DRD2SIGMAR1MEN1KMT2ASLC18A3 | |
| SCHEMBL4111754 | 0.71 | DRD2 (0.53) | DRD2SMN1; SMN2SIGMAR1MEN1KMT2A | |
| SCHEMBL1003503 | 0.71 | DRD2 (0.73) | DRD2SIGMAR1MEN1KMT2ATP53 | |
| SCHEMBL13197396 | 0.71 | RAB9A (0.54) | DRD2NPC1RAB9AMAPTSTAT1 | |
| SCHEMBL10264241 | 0.70 | LSS (0.59) | DRD2NPC1RAB9AMAPTSTAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409458-A1 | METHOD FOR PREPARING 4-AMINO-4-PHENYLPIPERIDINES | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008382-A1 | METHOD FOR PREPARING 4-AMINO-4-PHENYLPIPERIDINES | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |