SCHEMBL657406

SCHEMBL657406

CN(C)c1ccccc1C(c1ccccc1N(C)C)c1ccccc1N(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
ALDH1A1 P00352 4/20 0.43
GAA P10253 3/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
NSD2 O96028 1/20 0.42
EGFR P00533 1/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CHEK1 O14757 1/20 0.41
NEK2 P51955 1/20 0.41
LIMK1 P53667 1/20 0.41
DYRK1A Q13627 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
HTR6 P50406 1/20 0.38
EP300 Q09472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30125097 1.00 MAPT (0.43) MAPTALDH1A1GAATP53TSHR
SCHEMBL6247039 0.86 HTR2A (0.40) MAPTALDH1A1GAATP53TSHR
SCHEMBL5227537 0.82 GABRA1 (0.46) MAPTALDH1A1GAATP53TSHR
SCHEMBL3893551 0.82 MAPT (0.41) MAPTALDH1A1GAATP53TSHR
SCHEMBL1553187 0.80 MAPT (0.40) MAPTALDH1A1GAATP53TSHR
SCHEMBL11693922 0.80 MAPT (0.40) MAPTALDH1A1GAATP53TSHR
Hydrochloric Acid SCHEMBL2866667 0.80 GABRA1 (0.44) MAPTALDH1A1GAATP53TSHR
SCHEMBL5799083 0.80 MAPT (0.45) MAPTALDH1A1GAATP53TSHR
SCHEMBL9499214 0.80 NPSR1 (0.36) MAPTALDH1A1TSHRSMN1; SMN2KDM4E
SCHEMBL10926304 0.78 MAPT (0.43) MAPTALDH1A1GAATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7501172-B2 Integrated recording and labeling with optical recording device HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-03-10 US claimed
US-7172991-B2 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-02-06 US claimed
US-20060262178-A1 Integrated recording and labeling with optical recording device ANDERSON DARYL E 2006-11-23 US claimed
US-20030108708-A1 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. 2003-06-12 US claimed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US claimed
US-12559649-B2 Acrylate structural adhesive SCIGRIP ADHESIVES LTD. (GB) 2026-02-24 US disclosed
EP-4247909-B1 ACRYLATE STRUCTURAL ADHESIVE FREE OF MMA SCIGRIP ADHESIVES LTD (GB) 2026-01-28 EP disclosed
US-20250223389-A1 AUTONOMOUSLY CURABLE AND FOAMABLE TWO-COMPONET ACRYLIC ADHESIVE Rahme, Roland (FR) 2025-07-10 US disclosed
US-20250057868-A1 COMPOSITIONS AND METHODS OF MODULATING HIF-2A TO IMPROVE MUSCLE GENERATION AND REPAIR UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2025-02-20 US disclosed
EP-4493604-A1 AUTONOMOUSLY CURABLE AND FOAMABLE TWO-COMPONENT ACRYLIC ADHESIVE SciGrip Adhesives Ltd. (GB) 2025-01-22 EP disclosed
US-20240309249-A1 Acrylate Adhesive for Contact With Liquid Coolant SCIGRIP ADHESIVES LTD. (GB) 2024-09-19 US disclosed
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-07-23 US disclosed
WO-2003032299-A2 INTEGRATED CD/DVD RECORDING AND LABELING HEWLETT-PACKARD COMPANY (US) 2003-04-17 WO disclosed
EP-0889363-A1 Near IR sensitive photoimageable/photopolymerizable compositions, media, and associated processes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
US-5744280-A MONOCHROME IMAGES;IMPROVED CONTRAST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-28 US disclosed
EP-0828182-A1 Storage-stable photoimageable compositions with improved leuco dye E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-11 EP disclosed
EP-0491256-A1 Process for the preparation of triphenylmethane dyes BASF CORPORATION (US) 1992-06-24 EP disclosed
EP-0373438-A2 Photoresist film with a soluble intermediate layer BASF Aktiengesellschaft (DE) 1990-06-20 EP disclosed
EP-0156912-A1 TEMPERATURE SUPERVISION AND DISPLAY UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-10-09 EP disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057868-A1 COMPOSITIONS AND METHODS OF MODULATING HIF-2A TO IMPROVE MUSCLE GENERATION AND REPAIR HIF1A, HIF1AN, MYLK2 MAPT 4114/4885ALDH1A1 1579/4885GAA 977/4885
US-12559649-B2 Acrylate structural adhesive ICAM1, EPCAM, TAS2R42 MAPT 3184/4885ALDH1A1 28/4885GAA 4809/4885
US-12042507-B2 Compositions and methods of modulating HIF-2A to improve muscle generation and repair HIF1A, HIF1AN, MYLK2 MAPT 4114/4885ALDH1A1 1579/4885GAA 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.