Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685383 | 0.88 | TSHR (0.39) | TSHRKMT2AALDH1A1 | |
| SCHEMBL6577249 | 0.84 | OPRL1 (0.33) | OPRL1RIPK2 | |
| SCHEMBL8174171 | 0.78 | OPRL1 (0.36) | OPRL1KMT2AALDH1A1RIPK2GAA | |
| SCHEMBL8184433 | 0.78 | OPRL1 (0.36) | OPRL1KMT2AALDH1A1RIPK2GAA | |
| SCHEMBL7221242 | 0.78 | OPRL1 (0.39) | OPRL1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL7228348 | 0.77 | OPRL1 (0.35) | OPRL1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL7221508 | 0.77 | OPRL1 (0.43) | OPRL1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL6573291 | 0.77 | OPRL1 (0.38) | OPRL1 | |
| SCHEMBL7228623 | 0.77 | OPRL1 (0.44) | OPRL1OPRK1KCNH2ALDH1A1CYP2C9 | |
| SCHEMBL7222052 | 0.76 | OPRL1 (0.35) | OPRL1KMT2AALDH1A1RIPK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2004-04-07 | — | — | EP | disclosed |
| EP-0901490-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043286-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |