Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223809 | 0.85 | GRM5 (0.36) | OPRL1RIPK2CHEK1SLC6A4SLC6A3 | |
| SCHEMBL6573280 | 0.85 | SLC6A4 (0.37) | OPRL1RIPK2SLC6A4SLC6A3 | |
| SCHEMBL6574294 | 0.84 | OPRL1 (0.39) | OPRL1RIPK2 | |
| SCHEMBL8174171 | 0.82 | OPRL1 (0.36) | OPRL1RIPK2CHEK1CYP11B2 | |
| SCHEMBL8184433 | 0.82 | OPRL1 (0.36) | OPRL1RIPK2CHEK1CYP11B2 | |
| SCHEMBL6573291 | 0.81 | OPRL1 (0.38) | OPRL1SLC6A4SLC6A3CYP11B2 | |
| SCHEMBL6617335 | 0.81 | OPRL1 (0.41) | OPRL1CHEK1SLC6A4SLC6A3CYP11B2 | |
| SCHEMBL7222052 | 0.81 | OPRL1 (0.35) | OPRL1RIPK2CHEK1CYP11B2 | |
| SCHEMBL7952198 | 0.81 | GRM5 (0.41) | OPRL1RIPK2PDE4APDE4BPDE4C | |
| SCHEMBL8188621 | 0.80 | NPSR1 (0.34) | OPRL1RIPK2CHEK1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2004-04-07 | — | — | EP | disclosed |