Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541653 | 0.75 | NFE2L2 (0.42) | NFE2L2TRPA1CHATNR1H2CYP1A1 | |
| SCHEMBL541654 | 0.75 | NFE2L2 (0.42) | NFE2L2TRPA1CHATNR1H2CYP1A1 | |
| SCHEMBL56068 | 0.73 | PELI1 (0.41) | NFE2L2TRPA1CHATNR1H2CYP1A1 | |
| SCHEMBL56069 | 0.73 | PELI1 (0.41) | NFE2L2TRPA1CHATNR1H2CYP1A1 | |
| SCHEMBL2033487 | 0.73 | NFE2L2 (0.54) | NFE2L2TRPA1CHATCYP1A1CYP1A2 | |
| SCHEMBL2033485 | 0.73 | NFE2L2 (0.54) | NFE2L2TRPA1CHATCYP1A1CYP1A2 | |
| SCHEMBL478036 | 0.67 | NFE2L2 (0.58) | NFE2L2TRPA1CHATNR1H2MAOA | |
| SCHEMBL478037 | 0.67 | NFE2L2 (0.58) | NFE2L2TRPA1CHATNR1H2MAOA | |
| SCHEMBL11143726 | 0.67 | TRPA1 (0.53) | NFE2L2TRPA1LMNAPELI1 | |
| SCHEMBL1617410 | 0.66 | CYP1A2 (0.43) | NFE2L2TRPA1CHATSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027398-B1 | LIGHT-EMITTING DENDRIMERS AND DEVICES | ISIS INNOVATION (GB) | 2004-06-09 | — | — | EP | disclosed |