Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573906 | 0.92 | ADORA1 (0.56) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6572900 | 0.85 | ADORA1 (0.55) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6574601 | 0.85 | ADORA1 (0.55) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6573870 | 0.84 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6574578 | 0.83 | ADORA2A (0.60) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6572804 | 0.82 | ADORA2A (0.55) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6576712 | 0.82 | ADORA1 (0.55) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6663637 | 0.81 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6572865 | 0.81 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6878740 | 0.81 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AADORA2BPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | claimed |