Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067579 | 0.91 | ADORA3 (0.61) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6658486 | 0.90 | ADORA3 (0.76) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL14906549 | 0.84 | ADORA3 (1.00) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL13268988 | 0.83 | ADORA3 (0.98) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6660596 | 0.82 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL6660602 | 0.82 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BSLC29A1 | |
| SCHEMBL6660699 | 0.82 | ADORA3 (0.84) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6253676 | 0.81 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL7121616 | 0.81 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7064488 | 0.81 | ADORA3 (0.65) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030856-B1 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | claimed |