Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906926 | 1.00 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6906932 | 1.00 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6906923 | 1.00 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574649 | 0.84 | ADORA3 (0.70) | ADORA3ADORA1ADORA2AADORA2B | |
| Gw493838 SCHEMBL6935807 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| Gw493838 SCHEMBL29384676 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| Gw493838 SCHEMBL6696560 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| Gw493838 SCHEMBL6225102 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| Gw493838 SCHEMBL6250937 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6572751 | 0.81 | ADORA3 (0.71) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | claimed |
| JP-3378240-B2 | — | — | 2003-02-17 | — | — | JP | claimed |
| US-6492348-B1 | Adenosine derivatives | SMITHKLINE BEECHAM CORPORATION | 2002-12-10 | — | — | US | claimed |
| JP-2002518509-A | — | — | 2002-06-25 | — | — | JP | claimed |
| EP-1090019-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067262-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | claimed |
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-6492348-B1 | Adenosine derivatives | SMITHKLINE BEECHAM CORPORATION | 2002-12-10 | — | — | US | disclosed |
| EP-1090019-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067262-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | disclosed |