Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.70 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906932 | 0.84 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6906923 | 0.84 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6906926 | 0.84 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574632 | 0.84 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6572751 | 0.82 | ADORA3 (0.71) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6572766 | 0.82 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6575147 | 0.81 | ADORA3 (0.67) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6573000 | 0.81 | ADORA3 (0.67) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6664819 | 0.81 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BALDH1A1 | |
| SCHEMBL6661428 | 0.81 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |