Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | YWHAG | P61981 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574655 | 0.66 | POLB (0.46) | MAOBGFERMEN1KMT2APOLB | |
| SCHEMBL13269424 | 0.64 | CYP19A1 (0.52) | CYP19A1MAOAMAOBNPSR1FURIN | |
| SCHEMBL11883864 | 0.64 | CYP19A1 (0.52) | CYP19A1MAOAMAOBNPSR1FURIN | |
| SCHEMBL11883859 | 0.64 | CYP19A1 (0.52) | CYP19A1MAOAMAOBNPSR1FURIN | |
| Hydrochloric Acid SCHEMBL9324263 | 0.64 | POLB (0.54) | CYP19A1MAOAMAOBF2PLG | |
| SCHEMBL11957621 | 0.62 | CYP19A1 (0.54) | CYP19A1MAOAMAOBNPSR1FURIN | |
| Hydrochloric Acid SCHEMBL9324272 | 0.61 | FURIN (0.76) | F2FURIN | |
| SCHEMBL17285059 | 0.60 | G6PC1 (0.70) | CYP19A1MAOAMAOBMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL2947932 | 0.60 | FURIN (0.41) | FURINPOLB | |
| SCHEMBL7594901 | 0.58 | GRIN1 (0.47) | F2MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | claimed |
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
| US-6652600-B2 | Oxidation color dye | L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | KRT18, OGG1, UNG | CYP19A1 4380/4885MAOA 649/4885MAOB 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.