SCHEMBL6574668

SCHEMBL6574668

NC(=O)CC[C@H](NS(=O)(=O)c1ccccc1)C(=O)O

nearest known ligand 0.86

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 17/20 0.86
MMP2 P08253 16/20 0.86
MMP8 P22894 7/20 0.68
MMP13 P45452 1/20 0.68
ADAMTS4 O75173 1/20 0.68
MMP12 P39900 6/20 0.60
MMP14 P50281 6/20 0.60
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8507685 0.93 MMP9 (1.00) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL716323 0.88 MMP9 (0.86) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL698930 0.88 MMP9 (0.86) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL698929 0.88 MMP9 (0.86) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL21538609 0.87 MMP9 (0.76) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL3458998 0.87 MMP9 (0.76) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL14602295 0.86 MMP9 (0.86) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL9257772 0.85 MMP9 (0.73) MMP9MMP2MMP8MMP13ADAMTS4
Carglumic Acid SCHEMBL7824179 0.85 MMP9 (0.71) MMP9MMP2MMP8MMP13ADAMTS4
SCHEMBL5191062 0.84 MMP2 (0.63) MMP9MMP2MMP8MMP13ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1436371-A2 ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING Call, Krimhild (DE) 2004-07-14 EP claimed
WO-2002099023-A2 ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING CALL, KRIMHILD (DE) 2002-12-12 WO claimed
CN-116419926-A Serum albumin binding polypeptides 阿瓦克塔生命科学有限公司 2023-07-11 CN disclosed
CN-115990277-A Silica-based fluorescent nanoparticles 斯隆-凯特林癌症研究院 2023-04-21 CN disclosed
EP-1436371-A2 ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING Call, Krimhild (DE) 2004-07-14 EP disclosed
WO-2002099023-A2 ENZYMATIC SYSTEMS FOR GENERATING ACTIVE OXYGEN SPECIES FOR REACTING WITH OTHER PRECURSORS TO OBTAIN OXIDATION AND/OR BLEACHING CALL, KRIMHILD (DE) 2002-12-12 WO disclosed
EP-0120438-A1 Optical antipodes of 8-amino-2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinoline, process for its preparation and pharmaceutical compositions having an anti-depressive action containing it HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-03 EP disclosed