Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573049 | 0.93 | JAK2 (0.33) | ABL1ABCB1BCRALDH1A1JAK2 | |
| SCHEMBL7693189 | 0.89 | FCGR3B (0.36) | ABL1ABCB1BCRALDH1A1CYP3A4 | |
| SCHEMBL6572942 | 0.89 | APP (0.41) | ABL1ABCB1BCRALDH1A1MEN1 | |
| SCHEMBL6570876 | 0.87 | SRC (0.39) | KDRAURKBCYP3A4PIK3CDPIK3CA | |
| SCHEMBL6571323 | 0.86 | ALDH1A1 (0.35) | ABL1ALDH1A1JAK2JAK1TYK2 | |
| SCHEMBL6572585 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TYK2MEN1POLBMMP14 | |
| SCHEMBL6572728 | 0.84 | FCGR3B (0.38) | ABL1ALDH1A1MEN1POLBMMP14 | |
| SCHEMBL6572467 | 0.84 | ALDH1A1 (0.37) | ABL1ALDH1A1MEN1POLBMMP14 | |
| SCHEMBL6570957 | 0.82 | PTGER4 (0.40) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL6572249 | 0.81 | MAPT (0.44) | ALDH1A1KDRMEN1POLBMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |