Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7686623 | 0.98 | TDP1 (0.36) | TDP1TSHRPTGDR2RAB9AKDM4E | |
| SCHEMBL6570781 | 0.83 | TDP1 (0.60) | TDP1TSHRRAB9AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6570763 | 0.81 | TDP1 (0.58) | TDP1TSHRRAB9AKDM4ENPC1 | |
| SCHEMBL30075769 | 0.77 | TDP1 (0.50) | TDP1TSHRRAB9AKDM4ENPC1 | |
| SCHEMBL5828143 | 0.77 | TDP1 (0.58) | TDP1TSHRRAB9ANPC1KMT2A | |
| SCHEMBL2479814 | 0.77 | TDP1 (0.50) | TDP1TSHRRAB9AKDM4ENPC1 | |
| SCHEMBL453782 | 0.77 | TDP1 (0.56) | TDP1TSHRRAB9AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6574161 | 0.75 | ALDH1A1 (0.57) | TDP1TSHRRAB9AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6571929 | 0.75 | TDP1 (0.48) | TDP1TSHRRAB9AKDM4ENPC1 | |
| SCHEMBL6574765 | 0.74 | RELA (0.33) | TDP1TSHRPTGDR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |