Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 9/20 | 0.59 |
| ▸ | CDK2 | P24941 | 6/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.59 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.59 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.54 |
| ▸ | CDK9 | P50750 | 2/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | CCNH | P51946 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 5/20 | 0.49 |
| ▸ | CLK2 | P49760 | 5/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND3 | P30281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574922 | 0.85 | CDK1 (0.71) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6574956 | 0.81 | CDK1 (0.65) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6775420 | 0.76 | CCNE2 (0.63) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6770758 | 0.76 | CDK1 (0.56) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL25737311 | 0.76 | CDK1 (0.71) | CDK1CDK2CCNE1FLT3CDK5 | |
| SCHEMBL6770594 | 0.75 | CDK1 (0.55) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6576946 | 0.75 | CCNE2 (0.60) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL21635686 | 0.74 | CDK1 (0.69) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL21473890 | 0.74 | CDK1 (0.69) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6775328 | 0.74 | CDK1 (0.60) | CDK1CDK2CCNE1CCNE2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |