Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.65 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | CDK2 | P24941 | 6/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.56 |
| ▸ | CLK1 | P49759 | 6/20 | 0.55 |
| ▸ | CLK2 | P49760 | 6/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND3 | P30281 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CDK7 | P50613 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CCNH | P51946 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574922 | 0.89 | CDK1 (0.71) | CDK1FLT3CDK2CCNE1CCNE2 | |
| SCHEMBL6578423 | 0.86 | CDK1 (0.75) | CDK1CDK2CCNE1CCNA2CLK1 | |
| SCHEMBL6576348 | 0.86 | CDK1 (0.75) | CDK1CDK2CCNE1CCNA2CLK1 | |
| SCHEMBL6775420 | 0.83 | CCNE2 (0.63) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6770758 | 0.81 | CDK1 (0.56) | CDK1FLT3CDK2CCNE1CCNE2 | |
| SCHEMBL6574897 | 0.81 | CDK1 (0.59) | CDK1FLT3CDK2CCNE1CCNE2 | |
| SCHEMBL25737311 | 0.80 | CDK1 (0.71) | CDK1FLT3CDK2CCNE1CLK1 | |
| SCHEMBL6576946 | 0.80 | CCNE2 (0.60) | CDK1CDK2CCNE1CCNE2CCNA2 | |
| SCHEMBL6770594 | 0.80 | CDK1 (0.55) | CDK1FLT3CDK2CCNE1CCNE2 | |
| SCHEMBL25736248 | 0.80 | CDK1 (0.61) | CDK1FLT3CDK2CCNE1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |
| JP-2002537300-A | — | — | 2002-11-05 | — | — | JP | claimed |
| US-20020016329-A1 | 2-Amino-6-anilino-purines and their use as medicaments | NOVARTIS AG (CH) | 2002-02-07 | — | — | US | claimed |
| EP-1153024-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | Novartis AG (CH) | 2001-11-14 | — | — | EP | claimed |
| WO-2000049018-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016329-A1 | 2-Amino-6-anilino-purines and their use as medicaments | CDK14, CDK1, CCNB1 | CDK1 2/4885FLT3 357/4885CDK2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.