Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 16/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.60 |
| ▸ | CDK2 | P24941 | 16/20 | 0.60 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.60 |
| ▸ | CDK1 | P06493 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775420 | 0.89 | CCNE2 (0.63) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6576952 | 0.84 | CDK1 (0.74) | CCNE1CDK2CDK1 | |
| SCHEMBL6576948 | 0.84 | CDK1 (0.74) | CCNE1CDK2CDK1 | |
| SCHEMBL6770758 | 0.82 | CDK1 (0.56) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6574922 | 0.81 | CDK1 (0.71) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6770841 | 0.81 | CDK1 (0.55) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6574956 | 0.80 | CDK1 (0.65) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6770594 | 0.78 | CDK1 (0.55) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6775328 | 0.78 | CDK1 (0.60) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6775192 | 0.78 | CDK1 (0.54) | CCNE2CCNA2CCNE1CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |