Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574940 | 0.89 | OPRL1 (0.35) | OPRL1CHRNB2CHRNA4 | |
| SCHEMBL6573280 | 0.84 | SLC6A4 (0.37) | OPRL1CHRNB2CHRNA4SLC6A4SLC6A3 | |
| SCHEMBL6575137 | 0.83 | OPRL1 (0.33) | OPRL1CHRNB2CHRNA4 | |
| SCHEMBL6617335 | 0.82 | OPRL1 (0.41) | OPRL1CHRNB2CHRNA4SLC6A4SLC6A3 | |
| SCHEMBL7230266 | 0.82 | OPRL1 (0.44) | OPRL1CHRNB2CHRNA4SLC6A4SLC6A3 | |
| SCHEMBL7229847 | 0.80 | OPRL1 (0.42) | OPRL1SLC6A4SLC6A3 | |
| SCHEMBL6577249 | 0.79 | OPRL1 (0.33) | OPRL1SLC6A4SLC6A3 | |
| SCHEMBL6621538 | 0.79 | OPRL1 (0.33) | OPRL1SLC6A4SLC6A3 | |
| SCHEMBL6613896 | 0.78 | OPRL1 (0.37) | OPRL1CHRNB2CHRNA4SLC6A4SLC6A3 | |
| SCHEMBL6573291 | 0.78 | OPRL1 (0.38) | OPRL1CHRNB2CHRNA4SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2004-04-07 | — | — | EP | disclosed |