Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575048 | 0.87 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6575267 | 0.85 | ADORA1 (0.52) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6573870 | 0.85 | ADORA3 (0.60) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6576635 | 0.85 | ADORA1 (0.62) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6574578 | 0.84 | ADORA2A (0.60) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6573829 | 0.83 | ADORA1 (0.66) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6572804 | 0.83 | ADORA2A (0.55) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL10866451 | 0.81 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL8084006 | 0.81 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2BHIF1A | |
| SCHEMBL6660034 | 0.81 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2BHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |