Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572981 | 0.87 | PRKCI (0.41) | PTGER4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6575149 | 0.87 | FNTA (0.43) | PTGER4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6571957 | 0.86 | PRSS1 (0.38) | KDM4EALDH1A1HTTKMT2APRSS1 | |
| SCHEMBL6574696 | 0.85 | PTGER4 (0.68) | PTGER4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6570922 | 0.83 | PTGDR2 (0.44) | KDM4EALDH1A1GAAHPGDHTT | |
| Hydrochloric Acid SCHEMBL6573152 | 0.82 | PTGDR2 (0.43) | KDM4EALDH1A1GAAHPGDHTT | |
| SCHEMBL6571342 | 0.82 | USP7 (0.40) | KDM4EALDH1A1GAAMAPTTHRB | |
| SCHEMBL6571430 | 0.82 | PRSS1 (0.37) | ALDH1A1KMT2APRSS1PTGDR2 | |
| SCHEMBL6571545 | 0.81 | KDM4E (0.42) | PTGER4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6570671 | 0.81 | CYP1A2 (0.43) | KDM4EALDH1A1MAPTKMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |