Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.38 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.36 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.36 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571342 | 0.92 | USP7 (0.40) | PRSS1TDP1TSHRKDM4EALDH1A1 | |
| SCHEMBL6571430 | 0.91 | PRSS1 (0.37) | PRSS1FCGR3BFCGR1AFCGR2ATDP1 | |
| SCHEMBL6570671 | 0.90 | CYP1A2 (0.43) | PRSS1TDP1TSHRKMT2AKDM4E | |
| SCHEMBL6571157 | 0.90 | TDO2 (0.38) | PRSS1TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL6571420 | 0.90 | MKNK1 (0.37) | PRSS1TDP1TSHRKMT2AKDM4E | |
| SCHEMBL6572117 | 0.90 | FCGR3B (0.36) | PRSS1FCGR3BFCGR1AFCGR2ATDP1 | |
| SCHEMBL6573032 | 0.90 | ALDH1A1 (0.38) | PRSS1TDP1TSHRKMT2AKDM4E | |
| SCHEMBL6570922 | 0.90 | PTGDR2 (0.44) | TDP1KDM4EHTTALDH1A1TOP2B | |
| SCHEMBL6574148 | 0.88 | KDM4E (0.41) | PRSS1FCGR3BFCGR1AFCGR2AKDM4E | |
| Hydrochloric Acid SCHEMBL6573152 | 0.88 | PTGDR2 (0.43) | PRSS1TDP1KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |