Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818683 | 0.82 | ALDH1A1 (0.69) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL2395293 | 0.82 | POLB (0.55) | CA12CA9ALDH1A1KMT2AMAPT | |
| SCHEMBL16010335 | 0.81 | CA12 (0.71) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL522649 | 0.80 | CA12 (1.00) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL9617988 | 0.80 | ALDH1A1 (0.71) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL29744481 | 0.80 | CA12 (1.00) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL17560102 | 0.80 | ALDH1A1 (0.60) | CA12CA9ALDH1A1KMT2AMEN1 | |
| SCHEMBL2866490 | 0.80 | ALDH1A1 (0.55) | CA12CA9ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7085111 | 0.79 | CA12 (0.96) | CA12CA9ALDH1A1KMT2AMEN1 | |
| Phosphine SCHEMBL31113454 | 0.79 | CA12 (0.96) | CA12CA9ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974607-B1 | Coating compositions and inks | DU PONT (US) | 2004-09-29 | — | — | EP | claimed |
| EP-0974626-B1 | Aqueous pigmented ink jet inks for printing on vinyls | DU PONT (US) | 2004-05-19 | — | — | EP | claimed |
| EP-0826751-B1 | Aqueous dispersions containing graft copolymers as the dispersant | DU PONT (US) | 2004-04-28 | — | — | EP | claimed |
| EP-3189048-A1 | AMINOINDANE-, AMINOTETRAHYDRONAPHTHALENE- AND AMINOBENZOCYCLOBUTANE-DERIVED PRMT5-INHIBITORS | Ctxt Pty Ltd (AU) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016034671-A1 | AMINOINDANE-, AMINOTETRAHYDRONAPHTHALENE- AND AMINOBENZOCYCLOBUTANE-DERIVED PRMT5-INHIBITORS | CTXT PTY LTD (AU) | 2016-03-10 | — | — | WO | disclosed |
| CN-101981032-A | Substituted arylamide diaza pyrimidinone derivatives for the treatment of neurodegenerative diseases caused by abnormal activity of GSK 3-beta | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |
| US-5047259-A | For powder coating; long chain alkyl acrylates; solventless paint systems | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-09-10 | — | — | US | disclosed |