SCHEMBL6575589

SCHEMBL6575589

Nc1cc(N)c(NC(=O)Cn2cc[n+](CC(=O)Nc3c(N)cc(N)cc3O)c2)c(O)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RECQL P46063 1/20 0.37
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6571648 0.99 MEN1 (0.36) MEN1KMT2ARECQLLMNAALDH1A1
SCHEMBL6944197 0.85 LMNA (0.39) LMNA
SCHEMBL6573730 0.85 MEN1 (0.34) MEN1KMT2ARECQLLMNAALDH1A1
Hydrochloric Acid SCHEMBL6943223 0.84 LMNA (0.38) LMNA
Hydrochloric Acid SCHEMBL6575506 0.84 MEN1 (0.33) MEN1KMT2ARECQLLMNAALDH1A1
SCHEMBL6573847 0.83 MEN1 (0.42) MEN1KMT2ARECQLLMNAALDH1A1
Hydrochloric Acid SCHEMBL6574924 0.82 KMT2A (0.41) MEN1KMT2ARECQLLMNAALDH1A1
SCHEMBL6573686 0.82 RAD52 (0.39) MEN1KMT2ARECQLLMNAALDH1A1
Hydrochloric Acid SCHEMBL6572916 0.81 RAD52 (0.39) MEN1KMT2ARECQLLMNAALDH1A1
SCHEMBL6944662 0.78 KMT2A (0.54) MEN1KMT2ALMNAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP claimed
EP-1066263-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP claimed
WO-2000043368-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO claimed
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP disclosed
EP-1066263-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2001-01-10 EP disclosed
WO-2000043368-A1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS L'OREAL (FR) 2000-07-27 WO disclosed