SCHEMBL467266

SCHEMBL467266

CC1CN(Cc2ccccc2)CCC1=O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 6/20 0.62
LMNA P02545 2/20 0.62
ACHE P22303 2/20 0.51
SIGMAR1 Q99720 2/20 0.49
GRIN1 Q05586 1/20 0.49
GRIN2B Q13224 1/20 0.49
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MC4R P32245 1/20 0.46
GAA P10253 1/20 0.45
POLB P06746 1/20 0.45
BCHE P06276 1/20 0.44
BACE1 P56817 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6943959 1.00 TACR1 (0.62) TACR1LMNAACHESIGMAR1GRIN1
SCHEMBL385325 1.00 TACR1 (0.62) TACR1LMNAACHESIGMAR1GRIN1
Hydrochloric Acid SCHEMBL10382846 0.98 LMNA (0.64) TACR1LMNAACHESIGMAR1GRIN1
Iodide SCHEMBL8816299 0.98 TACR1 (0.61) TACR1LMNAACHESIGMAR1GRIN1
SCHEMBL20274753 0.86 ACHE (0.63) TACR1ACHESIGMAR1MC4RBCHE
SCHEMBL9466471 0.84 ACHE (0.54) TACR1LMNAACHESIGMAR1
SCHEMBL9379752 0.83 ACHE (0.50) TACR1LMNAACHESIGMAR1MC4R
SCHEMBL6230149 0.82 LMNA (0.46) TACR1LMNAACHEBCHE
SCHEMBL31193852 0.81 TACR1 (0.59) TACR1LMNAACHESIGMAR1GRIN1
SCHEMBL1339508 0.81 TACR1 (0.59) TACR1LMNAACHESIGMAR1GRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 891 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954807-A Method for preparing dihydrochloride of anticancer agent 昂克希尔迪克斯有限公司 2025-05-09 CN claimed
CN-118580192-A Preparation method of chiral intermediate of drug for treating ocular hypertension 安徽峆一药业股份有限公司 2024-09-03 CN claimed
CN-114957100-B Synthesis process of 1-benzyl-3-methyl-4-piperidone 苏州诚和医药化学有限公司 2023-04-14 CN claimed
CN-115010652-A Synthesis process of piperidine derivative intermediate 苏州诚和医药化学有限公司 2022-09-06 CN claimed
CN-114957100-A Synthesis process of 1-benzyl-3-methyl-4-piperidone 苏州诚和医药化学有限公司 2022-08-30 CN claimed
US-20260130907-A1 ALKYLAMINE-CONTAINING SMALL MOLECULE DEGRADERS OF BCL6 DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-14 US disclosed
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF INSILICO MEDICINE IP LTD (HK) 2026-01-08 US disclosed
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
US-12485144-B2 3-substituted piperidine compounds for Cbl-b inhibition, and use thereof NURIX THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
EP-4644396-A1 TOLL-LIKE RECEPTOR INHIBITOR, AND PREPARATION THEREFOR AND APPLICATION THEREOF Visionpharma (Nantong) Co., Ltd (CN) 2025-11-05 EP disclosed
CN-118580192-B Preparation method of chiral intermediate of drug for treating ocular hypertension 安徽峆一药业股份有限公司 2025-09-19 CN disclosed
EP-4616913-A2 GCN2 INHIBITORS AND USES THEREOF Merck Patent GmbH (DE) 2025-09-17 EP disclosed
EP-0106276-B1 1,4-DIHYDROPYRIDINE DERIVATIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-10-26 EP disclosed
US-4639522-A HYPOTENSIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 1987-01-27 US disclosed
US-4584303-A ANALGESICS THE BOC GROUP, INC. (US) 1986-04-22 US disclosed
EP-0160422-A1 N-Aryl-N-(4-Piperidinyl)amides and pharmaceutical compositions and methods employing such compounds Anaquest, Inc. (US) 1985-11-06 EP disclosed
EP-0156433-A2 Anti-virally active pyridazinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-10-02 EP disclosed
US-4481360-A 4H-1,2,4-Triazol-3-yl compounds THE UPJOHN COMPANY (US) 1984-11-06 US disclosed
EP-0106276-A2 1,4-Dihydropyridine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-04-25 EP disclosed
EP-0092391-A2 Novel piperidine derivatives and pharmaceutical compositions containing same KYOWA HAKKO KOGYO CO., LTD (JP) 1983-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008770-A1 CBL-B INHIBITORS AND METHODS OF USES THEREOF CBL, CBLC, CBLB TACR1 2886/4885LMNA 1902/4885ACHE 4588/4885
US-20260130907-A1 ALKYLAMINE-CONTAINING SMALL MOLECULE DEGRADERS OF BCL6 BCL6, BCL6B, BCL9L TACR1 1277/4885LMNA 983/4885ACHE 4882/4885
US-12485144-B2 3-substituted piperidine compounds for Cbl-b inhibition, and use thereof CBLB, CBL, CBLC TACR1 4881/4885LMNA 1711/4885ACHE 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.