Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 3/20 | 0.35 |
| ▸ | PGK2 | P07205 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154048 | 0.69 | TSHR (0.41) | KDM4ETDP1TSHRCYP2C19LMNA | |
| SCHEMBL17491576 | 0.69 | KDM4E (0.41) | KDM4ETDP1TSHRPGK1PGK2 | |
| SCHEMBL8373119 | 0.69 | TSHR (0.41) | KDM4ETDP1TSHRCYP2C19LMNA | |
| SCHEMBL8155737 | 0.69 | KDM4E (0.31) | KDM4ETDP1TSHR | |
| SCHEMBL8154487 | 0.69 | KDM4E (0.31) | KDM4ETDP1TSHR | |
| SCHEMBL8372978 | 0.69 | TSHR (0.41) | KDM4ETDP1TSHRCYP2C19LMNA | |
| SCHEMBL3244386 | 0.69 | LMNA (0.56) | KDM4ETDP1TSHRPGK1PGK2 | |
| SCHEMBL19959425 | 0.67 | KDM4E (0.35) | KDM4ETDP1TSHR | |
| Phosphoric Acid SCHEMBL28393093 | 0.67 | KDM4E (0.44) | KDM4ETDP1TSHRPGK1PGK2 | |
| SCHEMBL12994415 | 0.67 | ANPEP (0.38) | KDM4ETDP1TSHRPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000510455-A | — | — | 2000-08-15 | — | — | JP | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | claimed |
| EP-1386662-A1 | Double metal cyanide catalysts for preparing polyether polyols | Bayer Aktiengesellschaft (DE) | 2004-02-04 | — | — | EP | disclosed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |