Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155737 | 1.00 | KDM4E (0.31) | KDM4ETSHRTDP1 | |
| SCHEMBL8154976 | 1.00 | KDM4E (0.31) | KDM4ETSHRTDP1 | |
| SCHEMBL8154040 | 0.69 | LMNA (0.39) | — | |
| SCHEMBL8160584 | 0.69 | LMNA (0.39) | — | |
| SCHEMBL8155311 | 0.69 | LMNA (0.39) | — | |
| SCHEMBL6575853 | 0.69 | KDM4E (0.52) | KDM4ETSHRTDP1 | |
| SCHEMBL6448511 | 0.60 | — | — | |
| SCHEMBL27246 | 0.58 | — | — | |
| SCHEMBL6445135 | 0.58 | — | — | |
| SCHEMBL921572 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000510455-A | — | — | 2000-08-15 | — | — | JP | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | claimed |
| WO-1997039756-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | TROPONWERKE GMBH & CO. KG (DE) | 1997-10-30 | — | — | WO | claimed |
| EP-0896540-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | Troponwerke GmbH & Co. KG (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997039756-A1 | USE OF PHOSPHONIC ACID ESTERS FOR THE TREATMENT OF FUNCTIONAL DISORDERS OF THE BRAIN AND DEPRESSION | TROPONWERKE GMBH & CO. KG (DE) | 1997-10-30 | — | — | WO | disclosed |