Chloroform

Chloroform

SCHEMBL6575946

ClC(Cl)Cl.N=C(N)N

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL11792289 0.82
Chloroform SCHEMBL5612998 0.82
Guanidine SCHEMBL28432434 0.78
Guanidine SCHEMBL9794411 0.78
Guanidine SCHEMBL5613752 0.78
Guanidine SCHEMBL2003 0.78
Guanidine SCHEMBL29983942 0.78
Guanidine SCHEMBL165720 0.78 NOS2 (0.42)
Guanidine SCHEMBL11330173 0.78
SCHEMBL10676515 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689954-A A kind of hexazinone cleanly production technique 安徽广信农化股份有限公司 2018-10-23 CN claimed
CN-103755654-B A kind of synthesis technique of hexazinone ANHUI GUANGXIN AGRICULTURAL CHEMICALS CO., LTD. (CN) 2015-10-28 CN claimed
CN-103755654-A Synthetic process of hexazinone ANHUI GUANGXIN AGROCHEMICAL CO 2014-04-30 CN claimed
CN-108689954-A A kind of hexazinone cleanly production technique 安徽广信农化股份有限公司 2018-10-23 CN disclosed
CN-106596925-A Use of MMPs and TIMPs in screening of medicines for diagnosing or treating myocardial matrix reconstruction related diseases 广州市红十字会医院 2017-04-26 CN disclosed
CN-103755654-B A kind of synthesis technique of hexazinone ANHUI GUANGXIN AGRICULTURAL CHEMICALS CO., LTD. (CN) 2015-10-28 CN disclosed
CN-103755654-A Synthetic process of hexazinone ANHUI GUANGXIN AGROCHEMICAL CO 2014-04-30 CN disclosed
US-20040014947-A1 Novel human ependymin-like protein TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-01-22 US disclosed
US-6613887-B1 Of given amino acid sequence; nerve-extending activity; use as a therapeutic or prophylactic agent for Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, dementia TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-02 US disclosed
EP-0941246-A2 NOVEL PROTEIN, ITS PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1999-09-15 EP disclosed
WO-1998011130-A2 MAMMALIAN EPENDYMIN-LIKE PROTEINS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-19 WO disclosed