Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567255 | 0.91 | TYR (0.53) | LTA4HTSHRTYRMEN1TP53 | |
| SCHEMBL2412893 | 0.89 | LTA4H (0.47) | LTA4HALOX5 | |
| SCHEMBL6062066 | 0.88 | TYR (0.59) | LTA4HTSHRTYRMEN1TP53 | |
| SCHEMBL6061474 | 0.87 | CYP3A4 (0.62) | LTA4HTSHRTYRMEN1TP53 | |
| Ethylene Glycol SCHEMBL8027523 | 0.84 | TYR (0.46) | TSHRTYRMEN1TP53CYP3A4 | |
| Ethylene Glycol SCHEMBL8013191 | 0.84 | TYR (0.46) | TSHRTYRMEN1TP53CYP3A4 | |
| SCHEMBL6061193 | 0.83 | TYR (0.60) | LTA4HTSHRTYRMEN1TP53 | |
| SCHEMBL5208689 | 0.82 | ALOX5 (0.47) | LTA4HALOX5 | |
| SCHEMBL28981344 | 0.82 | LTA4H (0.42) | LTA4HTSHRTYRMEN1TP53 | |
| SCHEMBL27414383 | 0.82 | LTA4H (0.53) | LTA4HTYRMEN1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |